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硬化疗法系一种控制食道静脉曲张急性出血的安全简单方法。然而,本文患者用硬化疗法治疗4例发生急性肾功能衰竭。亲血色球蛋白系一种人类血浆内的糖蛋白,其可与过剩游离血红蛋白结合成复合物形式。从而抑制后者从肾小球的排泄。作者评价了亲血色球蛋白对硬化疗法所致肾脏损害的作用。 20例非酒精性肝硬化患者因食道静脉曲张而用硬化疗法治疗,随机分为在硬化疗法前一小时静脉输注亲血色球蛋白(4000u)或不用该药二组。二组年龄,性别或肝肾功能无显著差异。采用5％氨基乙醇油酸盐作硬化疗法。6侧对照者中2例发生血
Sclerotherapy is a safe and simple method of controlling acute bleeding of esophageal varices. However, patients treated with sclerotherapy in 4 patients developed acute renal failure. Pro-hemoglobin is a type of glycoprotein in human plasma that binds to excess free hemoglobin in the form of a complex. Thereby inhibiting the latter from the glomerular excretion. The authors evaluated the role of pro-hemoglobin in sclerosis-induced kidney damage. Twenty patients with non-alcoholic cirrhosis were treated with sclerotherapy due to esophageal varices and were randomized to either intravenous infusion (4000 u) of intravenous infusion of one hour before sclerotherapy or no drug. Two groups of age, gender or liver and kidney function no significant difference. 5% aminoethanol oleate for sclerotherapy. Two patients in 6 control subjects developed blood