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应用荧光偏振光技术对36例瘀症缺血性脑血管病(ICVD)和21例无瘀健康人的红细胞膜脂区微粘度进行比较,并用医学统计多因子逐步回归分析法对36例 ICVD 患者的微粘度与血液系统中16个血浆和全血因子进行相关分析。结果:(1)瘀症 ICVD 患者的红细胞膜脂区微粘度(3.55±0.21泊)明显高于无瘀健康人(2.770±0.12泊),P<0.001。(2)TCVD 患者的红细胞膜脂区微粘度与同时测定的红细胞电泳时间和高密度脂蛋白含量最为相关,前者呈正相关,而后者呈负相关。提示增加红细胞膜表面的流动性和增加高密度脂蛋白的浓度,对防治 ICVD 具有重要意义。
Fluorescence polarization technique was used to compare microviscosity of erythrocytes in 36 cases of ICVD and 21 cases of healthy people without blood stasis. 36 patients with ICVD were analyzed by multi-factor stepwise regression analysis The microviscosity was correlated with 16 plasma and whole blood factors in the blood system. Results: (1) Microviscosity (3.55 ± 0.21 poise) of erythrocyte membrane lipid in ICVD patients with stasis was significantly higher than that of healthy stools (2.770 ± 0.12 po), P <0.001. (2) The microviscosity of erythrocyte membrane lipids in TCVD patients was most closely correlated with the time of erythrocyte electrophoresis and the content of high density lipoprotein. The former was positively correlated, while the latter was negatively correlated. Prompted to increase the mobility of red blood cell membrane surface and increase the concentration of high-density lipoprotein, ICVD is of great significance.