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目的探讨早期足量胃肠外营养对早产低体重儿出院时体重的影响。方法随机将138例符合条件的早产低体重儿分为治疗组及对照组,治疗组早期足量胃肠外营养,对照组应用传统新生儿胃肠外营养。计算两组患儿平均住院时间、生理性体重下降持续平均时间、体重下降幅度及恢复出生体重的平均时间,两组患儿出院时宫外生长发育迟缓(EUGR)的发生率。结果与对照组比较,治疗组患儿平均住院时间缩短,生理性体重下降持续时间缩短,生后体重下降幅度低,出院时EUGR的发生率降低,差异有统计学意义,P<0.05。结论早期足量胃肠外营养,可降低早产低体重儿EUGR的发生率,提高临床治疗效果,为今后实现追赶性生长打下良好基础,未见明显副作用,临床应用安全有效,值得推广。
Objective To investigate the effect of early adequate parenteral nutrition on body weight of discharged preterm low birth weight children. Methods 138 cases of preterm low birth weight children were randomly divided into treatment group and control group, the treatment group early enough parenteral nutrition, the control group of traditional neonatal parenteral nutrition. The average length of hospital stay, the average duration of physiological weight loss, the weight loss, and the mean time to recovering weight were calculated. The incidences of ectopic growth retardation (EUGR) at discharge were compared between the two groups. Results Compared with the control group, the average length of stay of hospitalized children in the treatment group was shortened, the duration of physiological weight loss shortened, the weight loss rate after birth was lower, and the incidence of EUGR was lower at discharge. The difference was statistically significant (P <0.05). Conclusions Early adequate parenteral nutrition can reduce the incidence of EUGR in preterm low birth weight infants and improve the clinical therapeutic effect, laying a good foundation for the future catch-up growth without obvious side effects. The clinical application is safe and effective and worthy of promotion.