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以前单独给予糖尿病患者二甲双胍治疗,与磺脲类药物、胰岛素等传统降糖药物相比,糖尿病相关终点事件发生率降低了32%,全死因风险下降了36%。为何二甲双胍能更好地控制糖尿病风险?其心脏保护作用机制是
Previously, metformin alone was given to patients with diabetes. Compared with traditional hypoglycemic drugs such as sulfonylureas and insulin, the incidence of diabetes-related endpoints decreased by 32% and the risk of all-causes was reduced by 36%. Why metformin can better control the risk of diabetes? The mechanism of cardiac protection is