宫颈内放含前列腺素胶冻,已有效地用于早孕吸宫前扩张宫颈与足月妊娠时促使宫颈成熟。最近报道,宫颈内放Sulprostone胶冻可在数小时内使宫颈成熟,而用于足月引产。人们曾经推测前列腺素局部用药后迅速发生作用,这是由于蛋白溶解酶的作用,它可促使宫颈结缔组织的胶原变性。 Cervical containing prostaglandin jelly, has been effectively used for early pregnancy, aspiration of the uterus dilated cervix and full-term pregnancy to promote cervical ripening. Recently, Sulprostone jelly in the cervix has been shown to mature the cervix in a matter of hours for term term labor. It has been speculated that the rapid application of prostaglandin after topical effect, which is due to the role of proteolytic enzymes, it can promote cervical connective tissue collagen denaturation.