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睾丸女性化为男性假两性畸形,亦称雄激素不敏感综合征。胚胎期中肾管(即午非氏管)未向男性方向发展,副中肾管(即苗勒氏管)亦未发育,其外生殖器呈女性,睾丸仍未下降,位于阴唇或腹股沟处,无阴毛、腋毛。睾丸与正常一样分泌雄、雌激素,由于靶细胞缺乏雄激素受体所致。发生率在新生儿中约为0.083‰,有家族倾向。本院近年收治10例,现报告如下:
Testicular feminization of male pseudohermaphroditism, also known as androgen insensitivity syndrome. In the embryonic period, the renal tube (ie, Aflatoxedema) did not develop in the male direction. The secondary mesorectal tube (ie, Müllerian duct) was also not developed. The external genitalia was female and the testes had not dropped. They were located at the labia majora or groin, Pubic hair, armpit hair. Testicular secretion of male and female as normal, estrogen, the lack of androgen receptor due to target cells. The incidence of newborns in about 0.083 ‰, a family tendency. The hospital admitted to 10 cases in recent years, are as follows: