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目的：探讨原发性肝癌(HCC)患者经超低温超导系统氩氦刀治疗前、后，血清可溶性上皮钙粘蛋白(SE－Cadherin)水平变化。方法：用酶联免疫吸附双抗体夹心法检测19例HCC患者治疗前、治疗后，13例其他恶性肿瘤，19例正常健康体检人员血清SE－Cadherin水平。结果：HCC患者治疗前血清SE－Cadherin水平明显高于治疗后、其他恶性肿瘤组及正常对照组，其差异有显著意义(P＜0．01)。而治疗后、其他恶性肿瘤组及正常对照组之间无显著性差异(P＞0．05)。结论：超低温超导系统氩氦刀治疗HCC可使病情有所改善。
Objective: To investigate the changes of serum soluble cadherin (SE-Cadherin) levels in primary hepatocellular carcinoma (HCC) patients before and after treatment with cryogenic superconducting system argon-helium knife. Methods: Serum levels of SE-Cadherin in 19 patients with HCC before and after treatment were detected by enzyme-linked immunosorbent assay (ELISA), 13 other malignant tumors and 19 healthy controls. Results: The serum levels of SE-Cadherin in HCC patients before treatment were significantly higher than those in other malignant tumors and normal controls (P <0.01). After treatment, there was no significant difference between other malignant tumor group and normal control group (P> 0.05). Conclusion: The treatment of HCC with cryogenic superconducting system can improve the condition.