患者男,36岁,因腰部持续剧痛活动受限一月余入院。住院前三个月始无诱因腰部隐痛,日趋加重。外院查ESR 110mm/1h,腰椎摄片L_1呈轻度楔形改变,诊断为强直性脊椎炎,激素治疗无效。住院期间,逐渐出现胸骨、肋骨压痛,腰痛进行性加剧,并有齿龈出血。查体:T37.3℃。消瘦、贫血貌,胸骨压痛(+),心肺无异常发现,肝脾不大,L3、4、5叩痛(+),神经系检 Male patient, 36 years old, was admitted to hospital for more than one month because of persistent pain in his waist. Three months before admission, no incentive to waist pain, increasing. Outside the hospital check ESR 110mm / 1h, lumbar radiography L_1 showed a slight wedge-shaped change, the diagnosis of ankylosing spondylitis, hormone therapy is invalid. During hospitalization, there gradually sternum, rib tenderness, low back pain progressive, and bleeding gums. Physical examination: T37.3 ℃. Weight loss, anemia, chest tenderness (+), no abnormal heart and lung findings, hepatosplenism, L3,4,5 percussion pain (+), nervous system