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目的调查武汉市东西湖区与羊密切接触人群戊型肝炎病毒(HEV)感染状况并分析可能的危险因素,为戊型肝炎(HE)的预防控制提供依据。方法采集与羊密切接触人群和普通人群的血液样本,用酶联免疫吸附试验检测血清HEV-IgG;调查分析两组人群的基本情况和与羊密切接触人群感染HEV的危险因素。结果与羊密切接触人群血液样本145份、HEV-IgG阳性率53.79%,普通人群血液样本158份、HEV-IgG阳性率38.61%,两者差异具有统计学意义。结论武汉市东西湖区与羊密切接触人群HEV既往感染率明显高于普通人群,两者差异具有统计学意义,专职从事畜牧养殖和年龄较大是可能的危险因素。
Objective To investigate the status of hepatitis E virus (HEV) infection in people in close contact with Dongyang Lake in Wuhan and to analyze the possible risk factors for the prevention and control of hepatitis E (HE). Methods Blood samples were collected from close contact with sheep and the general population. Serum HEV-IgG was detected by enzyme-linked immunosorbent assay (ELISA). The prevalence of HEV-IgG in HEV-IgG infection group and the risk factors for HEV infection in sheep were investigated. Results There were 145 blood samples in close contact with sheep, the positive rate of HEV-IgG was 53.79%, the blood samples of 158 normal people and the positive rate of HEV-IgG were 38.61%, the difference was statistically significant. Conclusion The past infection rate of HEV in close contact with Dongyang Lake in Wuhan City was significantly higher than that in the general population. The difference between the two groups was statistically significant, and full-time livestock husbandry and older age were possible risk factors.