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肾上腺皮质激素(简称激素)是治疗免疫性肾脏病的主要药物,最常使用的激素是强的松,内科医生必须精通其临床应用的进展。作者复习了近年文献,结合个人经验,综述如下:一、皮质激素对免疫性肾脏病的作用机理在免疫性肾脏病中,强的松作用机制目前仍不十分清楚,但可以肯定的有以下两方面作用:①免疫抑制作用。激素能使血循环内 T 淋巴细胞和单核-巨噬细胞减少,功能降低,可影响 B 细胞的抗体生成,使免疫球蛋白及血补体水平降低,并减少肉芽肿的形
Corticosteroids (referred to as hormones) is the treatment of immune kidney disease, the main drug, the most commonly used hormone is prednisone, physicians must master the progress of its clinical application. The author reviewed the recent literature, combined with personal experience, summarized as follows: First, the mechanism of action of corticosteroids on immune nephropathy In immune nephropathy, the mechanism of action of prednisone is still not very clear, but you can be sure of the following two Aspects: ① immunosuppressive effect. Hormone can make the blood circulation of T lymphocytes and monocytes - macrophages decreased, reduced function, can affect the B cell antibody production, so that immunoglobulin and blood complement levels, and reduce the form of granuloma