论文部分内容阅读
目的:研究加味补中益气汤对慢性阻塞性肺疾病(COPD)稳定期生存质量的改善作用。方法:60例病情程度为Ⅱ级(中度)～Ⅲ级(重度)COPD稳定期患者随机分为中医组和西医对照组各30例。中医组予加味补中益气汤(组成:黄芪、甘草、红参、当归、川芎、橘皮、半夏、升麻、柴胡、茯苓、白术、桔梗、枳壳、杏仁、桃仁)口服,西医对照组予沙美特罗替卡松粉吸入剂吸入治疗,疗程2个月。测评治疗前后生存质量评分。结果:与本组治疗前比较,中医组生存质量总均分(TMS)、日常工作能力因子分(F1S)、社会活动状况因子分(F2S)、抑郁心理症状因子分(F3S)、焦虑心理症状因子分(F4S)均有显著下降(P<0.05,P<0.001),西医对照组TMS、F1S、F4S有显著下降(P<0.001),但F2S、F3S无显著下降(P>0.05);治疗前后评分差值比较,中医组TMS、F1S、F3S、F4S明显高于西医组(P<0.05,P<0.01,P<0.001),F2S差值无显著性差异(P>0.05)。结论:加味补中益气汤能有效改善COPD稳定期患者生存质量。
Objective: To study the effect of Jiaweibazhongyiqi decoction on improving the quality of life of chronic obstructive pulmonary disease (COPD) in stable phase. Methods: Sixty patients with grade Ⅱ (moderate) ~ Ⅲ grade (severe) stable COPD were randomly divided into two groups (n = 30 in each group) and control group (n = 30). The traditional Chinese medicine group was given oral administration of Bu Zhong Yi Qi Decoction (consisting of Astragalus membranaceus, Radix Glycyrrhizae, Radix Ginseng, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Orange Peel, Pinellia tuber, Cimicifuga fascia, Poria cocos, Atractylodes macrocephala, Western control group to salmeterol fluticasone powder inhalation inhalation therapy, treatment of 2 months. Assessment of quality of life before and after treatment score. Results: Compared with the pretreatment group, TMS, F1S, F2S, F3S, anxiety and psychological symptoms (P <0.05, P <0.001). The levels of TMS, F1S and F4S in Western medicine group were significantly decreased (P <0.001), but there was no significant decrease in F2S and F3S (P> 0.05) There was no significant difference in F2S between TMS, F1S, F3S and F4S in TCM group (P <0.05, P <0.01, P <0.001). Conclusion: Jia Bu Bu Zhong Yi Qi Tang can effectively improve the quality of life in patients with stable COPD.