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目的:研究奥美拉唑联合阿莫西林在临床上治疗胃溃疡的有效率和安全性。方法:选择我院2016年2月2017年2月收入的62例胃溃疡患者随机数字法分为观察组和对照组两组,两组均接受一般支持治疗,观察组服用奥美拉唑加阿莫西林,对照组服用西咪替丁和硫糖铝。2周后分别观察两组疗效和不良反应。结果:观察组治疗总有效率93.55%远远高于对照组77.42%,且差异具有统计学意义(P<0.05),观察组不良反应发生率9.68%远低于对照组不良反应发生率25.81%,组间差异具有统计学意义(P<0.05)。结论:奥美拉唑结合阿莫西林治疗胃溃疡有效率较高,且安全性较高,可以在临床上推广使用。
Objective: To study the efficacy and safety of omeprazole combined with amoxicillin in the treatment of gastric ulcer in clinic. Methods: Sixty-two patients with gastric ulcer whose income was collected in February 2016 and February 2017 in our hospital were randomly divided into observation group and control group. Both groups received general supportive therapy. The observation group took omeprazole plus Moxillin, the control group taking cimetidine and sucralfate. After 2 weeks, the curative effect and side effect of two groups were observed respectively. Results: The total effective rate of observation group was 93.55%, which was significantly higher than that of control group (77.42%), and the difference was statistically significant (P <0.05). The adverse reaction rate in observation group was 9.68%, which was much lower than that in control group (25.81% , The difference between the groups was statistically significant (P <0.05). Conclusion: Omeprazole combined with amoxicillin in the treatment of gastric ulcer is more effective and safe, and can be widely used in clinic.