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膀胱移行上皮细胞癌(TCC)患者的血清和尿中癌胚抗原(CEA)增多,但CEA增多的程度是否同肿瘤的分级、分期有关,报道不很一致。本文用组织学和免疫细胞化学方法,直接对150例TCC患者的肿瘤组织进行了CEA检查。受检病例均经尿道取得标本,Ⅰ、Ⅱ、Ⅲ级肿瘤各为50例。根据UICC分类法,将TCC分为四期:肿瘤组织仅限于乳头,尚无浸润蔓延者为pTA,肿瘤组织局限于粘膜内者为pT_1,肿瘤组织侵及表层肌者为pT_2,肿瘤组织侵及深层肌者为pT_3(本文pT_2和pT_3合并分析)。Ⅰ级TCC患者中pTA39例,pT_110例,pT_(2/3)1例;Ⅱ级TCC患者中pTA16例,pT_117例,pT_(2/3)17例;Ⅲ级TCC患者中pTA_1例,pT_112例,pT_(2/3)37例。
The serum and urinary carcinoembryonic antigen (CEA) increased in patients with bladder transitional cell carcinoma (TCC), but whether CEA increased was related to tumor grade and stage, and the reports were not consistent. In this paper, histological and immunocytochemical methods directly to 150 cases of TCC patients with tumor tissue CEA examination. The specimens were obtained through the urethra specimens, Ⅰ, Ⅱ, Ⅲ grade tumors were 50 cases. According to the UICC classification, TCC is divided into four phases: tumor tissue is confined to the papilla, no invasive infiltration is pTA, tumor tissue confined to the mucosa is pT_1, the tumor tissue invading the superficial muscle is pT_2, the tumor tissue invading Deep muscle was pT_3 (this paper pT_2 and pT_3 merge analysis). Grade Ⅰ TCC patients with pTA39 cases, pT_110 cases, pT_ (2/3) in 1 case; Ⅱ grade TCC patients pTA16 cases, pT_117 cases, pT_ (2/3) 17 cases; Ⅲ grade TCC patients pTA_1 cases, pT_112 cases , pT_ (2/3) 37 cases.