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目的:探讨婴幼儿肺炎血清心肌酶谱变化与病情的关系。方法:选择有并发症婴幼儿肺炎25例(重症组)、无并发症肺炎32例(轻症组)和无肺、心、脑疾病20例(对照组),采用酶动力学速率法检测各组急性期与恢复期血清心肌酶谱活性,并相互比较。结果:轻、重症组急性期心肌酶谱活性升高,与对照组比较有显著差异(P<005,P<001),且轻、重症两组比较有显著性差异(P<005,P<001);恢复期心肌酶谱活性下降正常,各组间无显著性差异(P>005)。结论:婴幼儿肺炎心肌酶谱活性与病情密切相关,监测心肌酶谱变化对估价病情、指导治疗有重要意义。
Objective: To investigate the relationship between serum myocardial enzymes and infant’s pneumonia. Methods: Twenty-five infants and young children with severe complications (severe group), 32 with no complication pneumonia (mild group) and 20 without lung, heart and brain disease (control group) were enrolled in this study. Enzyme kinetic rate method Group acute and convalescent serum myocardial enzyme activity, and compared with each other. Results: Myocardial zymogram activity in acute and severe cases was significantly higher than that in control group (P <005, P <001), and there was significant difference between mild and severe cases (P < 0 05, P <0 01); recovery of myocardial enzyme activity decreased normal, no significant difference between the groups (P> 0 05). Conclusion: The activity of myocardial enzymes in infants with pneumonia is closely related to the disease. It is of great significance to monitor the change of myocardial enzymes to evaluate the condition and guide the treatment.