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甲砜霉素(Thiophenicol或Thiamphenicol)是一种合成的广谱抗菌素,结构与氯霉素相似,其抗菌谱也和氯霉素基本相同,但氯霉素在体内能与葡萄糖醛酸结合,以“失活”型排出,故不适用于尿路感染,而甲砜霉素在体内很少失活,并且氯霉素24小时尿中排泄量仅为口服量的8.2～10.1％,而甲砜霉素则高达43.8～66.9％,故可望用于治疗尿路感染。
Thiophenicol (Thiophenicol or Thiamphenicol) is a synthetic broad-spectrum antibiotic, similar to chloramphenicol in antibacterial spectrum and chloramphenicol, but chloramphenicol can be combined with glucuronic acid in the body to “Inactivate” type of discharge, it is not suitable for urinary tract infections, and thiamphenicol rarely inactivated in the body, and 24 hours urinary chloramphenicol excretion of oral only 8.2 to 10.1%, while the methyl sulfone As high as 43.8 to 66.9%, so is expected to be used for the treatment of urinary tract infections.