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由于文献上对宫体癌病人应用术前放疗能否降低阴道复发率及改善五年生存率意见不统一。作者对1954～1974年间接受治疗的463例宫体癌进行检查。其中181例进行术前放疗,282例在手术后补充放疗。作者术前镭疗所用镭量为2,000mghr,上镭后7天即行手术。结果发现这两组在五年生存率上并无差别(75%:74%)。而术前镭疗组的阴道复发率则显著低于术后放疗组(1.7%:7.4%)(P<0.05)。这与文献上大多数报告结果相类似,只有De Waal的报告相反,术前镭疗组阴道复发率为4.3～5.7%,而术后放疗组为0～1.7%。作者认为这是由于术前镭疗所使用的剂量以及镭疗后施行手术的间隔时间不同有关。通过术前镭疗(包括宫腔及阴道内镭疗)可使肿瘤细胞活性降低,从而可避免
As the literature on the application of preoperative radiotherapy for patients with uterine cancer can reduce the recurrence rate of vagina and improve the five-year survival rate of opinion is not uniform. The authors examined 463 cases of uterine cancer treated between 1954 and 1974. Of these, 181 received preoperative radiotherapy and 282 received postoperative radiotherapy. Radiotherapy preoperative radium used by the amount of 2,000mghr, 7 days after radium surgeries. The results showed no difference between the two groups in the five-year survival rate (75%: 74%). Vaginal recurrence rate in preoperative radiotherapy group was significantly lower than that in postoperative radiotherapy group (1.7% vs 7.4%, P <0.05). This is similar to most reports in the literature, only De Waal’s report contrasts with a 4.3% to 5.7% vaginal recurrence rate in preoperative radiotherapy versus 0% to 1.7% in postoperative radiotherapy. The authors believe this is due to the different doses used for preoperative radiotherapy and the time between radiotherapy and surgery. Preoperative radiotherapy (including intrauterine and intravaginal radium therapy) can reduce tumor cell activity, which can be avoided