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目的观察甲砜霉素治疗细菌性阴道病的有效性。方法将260例细菌性阴道病患者随机分为甲砜霉素组与甲硝唑组各130例,甲砜霉素组给予甲砜霉素0.5 g,3次/d口服;甲硝唑130例给予甲硝唑0.2 g,3次/d口服,两组连续用药7 d,停药3 d后复查,并观察其不良反应。结果甲砜霉素组治疗细菌性阴道病的总有效率为95.38%,甲硝唑组治疗细菌性阴道病的总有效率为93.07%,二者差异无统计学意义(P>0.05),甲砜霉素组的不良反应明显少于甲硝唑组差异有统计学意义(P<0.01)。结论甲砜霉素治疗细菌性阴道病安全有效,不良反应小。
Objective To observe the effectiveness of thiamphenicol in the treatment of bacterial vaginosis. Methods 260 patients with bacterial vaginosis were randomly divided into thiamphenicol group and metronidazole group of 130 cases, thiamphenicol group was given thiamphenicol 0.5 g, 3 times / d orally; metronidazole 130 cases Given metronidazole 0.2 g, 3 times / d orally, two groups of continuous medication 7 d, withdrawal 3 d after the review, and observe the adverse reactions. Results The total effective rate of thiamphenicol in treating bacterial vaginosis was 95.38%. The total effective rate of metronidazole in treating bacterial vaginosis was 93.07%. There was no significant difference between the two groups (P> 0.05) The adverse reaction of thiamphenicol group was significantly less than that of metronidazole group (P <0.01). Conclusion Thiamphenicol is safe and effective in the treatment of bacterial vaginosis with small adverse reactions.