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目的:探讨超声引导下疤痕子宫切口妊娠囊内注射MTX联合米非司酮口服的疗效。方法:选取我院2014年3月-2016年9月收治的疤痕子宫切口患者56例,随机将患者分为观察组和对照组,观察组患者28例,观察组患者使用囊内注射MTX联合米非司酮进行治疗;对照组患者28例,对照组患者仅使用囊内注射MTX进行治疗,对两组患者的临床治疗效果、β-HCG转阴时间、包块消失时间和阴道出血量进行比较。结果:经过实验研究可知,观察患者痊愈例数为27例,未治愈例数为1例,治愈率为96.43%;对照组患者痊愈例数为18例,未治愈例数为10例,治愈率为64.29%,观察组患者的治愈率明显高于对照组(P<0.05),呈现临床不均衡性;观察组患者在β-HCG转阴时间、包块消失时间和阴道出血量均明显少于对照组,并且P<0.05,具有统计学意义。结论:超声引导下疤痕子宫切口妊娠囊内注射MTX联合米非司酮口服的临床效果较好,患者β-HCG转阴时间和包块消失较短,阴道出血量较少。
Objective: To investigate the curative effect of intralesional injection of MTX combined with mifepristone under ultrasound-guided uterine scar incision. Methods: Fifty-six patients with scar hysterectomy admitted from March 2014 to September 2016 in our hospital were randomly divided into observation group and control group. 28 cases in observation group were treated with MTX in combination with rice In the control group, 28 patients in the control group were treated with intrathecal injection of MTX only. The clinical outcomes, β-HCG negative conversion time, disappearance of mass, and vaginal bleeding in both groups were compared . Results: The experimental study shows that the number of patients cured observed in 27 cases, the number of cases of non-cured cases was 1, the cure rate was 96.43%; the control group of patients cured cases were 18 cases, the number of cases of non-cured 10 cases, the cure rate (64.29%). The cure rate in the observation group was significantly higher than that in the control group (P <0.05), showing the clinical imbalance. The observation group had significantly less time of β-HCG negative conversion, the disappearance of mass and vaginal bleeding Control group, and P <0.05, with statistical significance. CONCLUSION: Ultrasound-guided intrauterine injection of MTX combined with mifepristone in pregnant women with uterine scar incision has good clinical effect. The time and mass disappearance of β-HCG in patients undergoing uterine incision are shorter, and the amount of vaginal bleeding is less.