药物洗脱支架能有效减少支架再狭窄和靶血管再次血运重建,然而,与金属裸支架比较,药物洗脱支架术后晚期血栓发生率呈上升趋势。研究显示支架术后再内皮化延迟与晚期血栓发生密切相关。内皮化程度是组织学上预测支架晚期血栓发生的重要指标,而内皮祖细胞是再内皮化过程的关键因素之一。因此,促进内皮祖细胞再内皮化可显著降低由支架损伤引起的晚期血栓发生。 However, compared with bare metal stents, the incidence of late thrombosis after drug-eluting stents is on the rise. Studies have shown that the delayed re-endothelialization and stent thrombosis are closely related. Endothelialization is an important index for histologically predicting the occurrence of late stent thrombosis, and endothelial progenitor cells are one of the key factors in reendothelialization. Therefore, promoting endothelial endothelial progenitor cells can significantly reduce stent injury caused by advanced thrombosis.