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目的毛细支气管炎是婴幼儿冬春季多发病、常见病,尤其是重症患儿疗效不尽人愿。本文旨在探讨在常规治疗的基础上加用果糖二磷酸钠治疗毛细支气管炎的疗效。方法对2005年11月～2007年11月在我科住院的重症毛细支气管炎120例,随机分为两组;治疗组和观察组。治疗组在常规治疗的基础上加用果糖二磷酸钠,观察两组疗效。结果治疗组60例,总有效56例(93.3%);观察组60例:总有效44例(73.3%)。卡方检验,x2=3.92,P<0.05,治疗组明显优于对照组。结论重症毛细支气管炎在常规治疗的基础上应用果糖二磷酸钠,可迅速改善喘憋症状,肺部罗音较快消失,其他症状亦可得以控制。其作用与其改善人体细胞代谢,保护受损细胞,有益于缺氧状态下细胞能量和葡萄糖利用有关;亦可能与改善磷酸盐消耗有关。
The purpose of bronchiolitis is infants and young children more common in winter and spring, common disease, especially in children with severe pain efficacy. This article aims to explore the treatment of bronchiolitis with the addition of sodium fructose diphosphate on the basis of conventional treatment. Methods 120 cases of severe bronchiolitis hospitalized in our department from November 2005 to November 2007 were randomly divided into two groups: treatment group and observation group. The treatment group was given sodium fructose diphosphate on the basis of routine treatment, and the curative effect was observed. Results The treatment group 60 cases, the total effective 56 cases (93.3%); observation group 60 cases: the total effective 44 cases (73.3%). Chi-square test, x2 = 3.92, P <0.05, the treatment group was significantly better than the control group. Conclusion Severe bronchiolitis is a common treatment based on the application of sodium fructose diphosphate, can quickly improve the symptoms of wheezing, pulmonary rales quickly disappear, other symptoms can be controlled. Its role and improve its metabolism of human cells to protect damaged cells, hypoxic cells beneficial to the energy and glucose utilization; may also be related to the improvement of phosphate consumption.