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目的:探讨氧氟沙星凝胶填充联合泪道探通术治疗新生儿泪囊炎的临床疗效。方法:将112例新生儿泪囊炎患者随机分为两组,观察组(56例)采用氧氟沙星凝胶填充联合泪道探通术治疗,对照组(56例)采用泪道探通术治疗,比较两组的临床疗效。结果:观察组痊愈54例,有效2例,痊愈率96.43%,对照组痊愈47例,有效6例,无效3例,痊愈率83.93%,观察组疗效优于对照组(Z=-2.244,P=0.025);观察组1例发生泪小点轻度撕裂,不良反应发生率1.79%,对照组2例发生泪小点轻度撕裂,1例形成假道,1例有窒息现象,不良反应率7.14%,两组不良反应率差异无统计学意义(χ2校正=0.837,P=0.360)。结论:氧氟沙星凝胶填充联合泪道探通术治疗新生儿泪囊炎效果好,有重要临床参考价值。
Objective: To investigate the clinical efficacy of ofloxacin gel filling combined with lacrimal passage exploration in the treatment of neonatal dacryocystitis. Methods: 112 cases of neonatal dacryocystitis were randomly divided into two groups. The observation group (56 cases) was treated with ofloxacin gel filling combined with lacrimal duct exploration. The control group (56 cases) Surgery, the clinical efficacy of the two groups were compared. Results: In the observation group, 54 cases were cured, 2 cases were effective and the cure rate was 96.43%. In the control group, 47 cases were cured, 6 cases were effective, 3 cases were ineffective and the cure rate was 83.93%. The curative effect in observation group was better than that in control group (Z = -2.244, P = 0.025). In the observation group, mild tear of punctum was observed in 1 case, and the incidence of adverse reactions was 1.79%. In the control group, mild tear in punctate tears occurred in 1 case, asphyxiation in 1 case, asphyxia in 1 case, The response rate was 7.14%. There was no significant difference in adverse reaction rate between two groups (χ2 correction = 0.837, P = 0.360). Conclusion: Ofloxacin gel filling combined with lacrimal duct exploration is effective in treating neonatal dacryocystitis and has important clinical reference value.