一般认为膜性肾小球肾炎(MGN)的肾小球损害是由小型的循环抗原——抗体(Ag-Ab)复合物沿着基底膜(GBM)上皮细胞侧呈线状沉积所引起。虽然迄今的报导中,大多数MGN被描述为“特发性”。但越来越多的证据证明MGN可能是由多种抗原所引起。对以往15年内的85例MGN患儿随访了一年以上。其中30例有肾外或肾小球外的疾患。本文目的介绍此30例儿童的临床经过并讨论每种伴随疾病与肾小球疾病的关系。肝炎和/或HBsAg携带急性肝炎:5例有水肿及严重肾病综合征患者被评定有轻症肝炎,他们均有肝肿大及转氨酶中度升高,其中2例有轻度黄疸伴高胆红质血症。作者认 Glomerular damage of membranous glomerulonephritis (MGN) is generally thought to be caused by the linear deposition of small circulating antigen-antibody (Ag-Ab) complexes along the epithelial cell side of the basement membrane (GBM). Although so far reported, most MGNs are described as “idiopathic.” However, there is growing evidence that MGN may be caused by a variety of antigens. 85 cases of MGN in the past 15 years follow-up of more than one year. Thirty of them had nephrotic or glomerular disorders. This article describes the clinical course of the 30 children and discusses the relationship between each comorbid disorder and glomerular disease. Hepatitis and / or HBsAg Acute Hepatitis: 5 patients with edema and severe nephrotic syndrome were evaluated as having mild hepatitis with moderate hepatomegaly and elevated transaminases, 2 of whom had mild jaundice with hyperbilirubinemia Hemolytic disease. The author recognizes