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目的观察无创正压通气治疗呼吸衰竭的临床疗效。方法选取2012年6月—2015年1月开远市解放军第59医院收入的呼吸衰竭患者78例,采用随机数字表法分为观察组和对照组,各39例。观察组患者给予无创正压通气治疗,对照组患者给予有创通气治疗,比较两组患者动脉二氧化碳分压(Pa CO2)、动脉血氧分压(Pa O2)、呼吸频率、心率、p H值及呼吸机相关性肺炎(VAP)发生率。结果两组患者治疗前Pa CO2、Pa O2、呼吸频率、心率、p H值比较,差异均无统计学意义(P>0.05);观察组患者治疗后Pa CO2、呼吸频率、心率均低于对照组,Pa O2高于对照组(P<0.05);两组患者治疗后p H值比较,差异无统计学意义(P>0.05)。观察组患者VAP发生率低于对照组(χ2=6.325,P=0.036)。结论无创正压通气可改善呼吸衰竭患者血气指标,且VAP发生风险低。
Objective To observe the clinical efficacy of non-invasive positive pressure ventilation in the treatment of respiratory failure. Methods From June 2012 to January 2015, 78 patients with respiratory failure in the 59th hospital of People’s Liberation Army in Kaiyuan City were selected and randomly divided into observation group and control group with 39 cases in each group. Patients in the observation group received noninvasive positive pressure ventilation and patients in the control group received invasive ventilation. PaCO 2, Pa O 2, respiration rate, heart rate and p H were compared between the two groups And ventilator-associated pneumonia (VAP) incidence. Results There was no significant difference in PaCO 2, Pa 2 O, respiration rate, heart rate and p H between the two groups before treatment (P> 0.05). PaCO 2, respiration rate and heart rate were lower in the observation group than those in the control group Group, Pa O2 was higher than that of the control group (P <0.05). There was no significant difference in p H between the two groups after treatment (P> 0.05). The incidence of VAP in observation group was lower than that in control group (χ2 = 6.325, P = 0.036). Conclusion Non-invasive positive pressure ventilation can improve blood gas index in patients with respiratory failure, and the risk of VAP is low.