血管性假血友病是一种由于遗传性皮肤、粘膜毛细血管缺陷所引起的出血性疾病,在男女两性中均可发生,约半数病例家族中有出血倾向病史,缺陷因子可能是通过单纯性显性遗传的(Simple do-minat),此病的基本缺陷尚未完全明了,组织学研究不能启示血管壁内有任何重要改变,然而应用毛细血管显微镜检查常可观察到患者甲床的毛细血管显示奇怪的、紊乱的形状,并于针刺后不见收缩。临床表现:本病多于幼年或青年时期发病,自发性出血通常限于鼻衄及齿龈出血,少数严重病例也可发生胃肠道及泌尿道出血。皮肤及 Von Willebrand disease is a hemorrhagic disease caused by genetic skin and mucosal capillary defects that can occur in both men and women. About half of the cases have a history of bleeding, and the defect factor may be caused by simplex Simple do-minat, the basic flaw of the disease is not yet fully understood, histological studies can not suggest any major changes in the vessel wall, but capillary capillaries can often be observed in patients with the application of capillary microscopy Strange, disorganized shape and no contraction after acupuncture. Clinical manifestations: The disease is more than the onset of childhood or youth, spontaneous bleeding is usually limited to epistaxis and bleeding gums, a few serious cases of gastrointestinal and urinary tract hemorrhage can occur. Skin and