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目的探讨磁共振扩散加权成像(DWI)和表观扩散系数(ADC)在肝脏恶性肿瘤诊断中的价值。方法 73例经临床证实的肝脏恶性肿瘤患者为病例组,以20例正常肝脏者为对照组,分析病例组及对照组的DWI图像并测量其ADC值。结果病例组73例均表现不同程度扩散受限,对照组无扩散受限。DWI检出肝脏恶性肿瘤的敏感度为100%。病例组ADC值(0.835±0.459)×10-3mm2/s,显著低于对照组ADC值(1.486±0.459)×10-3mm2/s(P<0.01),其中转移性肿瘤ADC值(0.699±0.198)×10-3mm2/s低于肝脏原发恶性肿瘤ADC值(0.922±0.658)×10-3mm2/s(P<0.01)。结论磁共振DWI和ADC值在肝脏恶性肿瘤的检出中有重要的临床意义。
Objective To investigate the value of diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) in the diagnosis of hepatic malignancies. Methods 73 patients with clinically confirmed liver malignant tumor were selected as the case group and 20 normal liver as the control group. The DWI images of the case group and the control group were analyzed and their ADC values were measured. Results The cases of 73 cases showed varying degrees of diffusion limited, the control group without diffusion limited. The sensitivity of DWI in detecting liver malignancies was 100%. The ADC value was 0.835 ± 0.459 × 10-3mm2 / s in case group, which was significantly lower than that in control group (1.486 ± 0.459 × 10-3mm2 / s, P <0.01). The ADC value of metastatic tumor was 0.699 ± 0.198 ) × 10-3mm2 / s was lower than the ADC value of primary liver cancer (0.922 ± 0.658) × 10-3mm2 / s (P <0.01). Conclusion MRI DWI and ADC values in the detection of liver malignancies have important clinical significance.