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测定了诺卡氏菌（Ｎｏｃａｒｄｉａ）、分枝杆菌（Ｍｙｃｏｂ ａｃｔｅｒｉｕｍ）和节杆菌（Ａｒｔｈｒｏｂ ａｃｔｅｒ）对大豆甾醇的降解能力及Ｎｉ２＋，Ｃｏ２＋，Ｍｎ２＋，α、α’－联吡啶、邻菲罗琳等酶抑制剂对△１，４－雄甾二烯－３， １７－二酮（ＡＤＤ）积累的影响．实验结果表明：节杆菌 Ａ－６在６０× １０－６硫酸镍存在下，使大豆甾醇的转化率达７０％以上，ＡＤＤ产率达３０％左右。
The degradation of soybean sterol by Nocardia, Mycob acterium and Arthrobacter and the degradation of Ni2 +, Co2 +, Mn2 +, α, α’-bipyridyl, Effect of Enzyme Inhibitors on the Accumulation of △ 1,4-androstadien-3,17-dione (ADD). The experimental results show that Arthrobacter A-6 in the presence of 60 × 10-6 nickel sulfate so that the conversion of soya sterol over 70%, ADD yield of about 30%.