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神经元特异性烯醇化酶(NSE)是主要存在于大脑神经元和神经内分泌细胞内(占99％),参与糖酵解的催化酶,神经元损伤或坏死后NSE则进入脑背液和透过血脑屏障进入血液。脑胶质细胞和其他组织不含NSE,故NSE是检测脑内神经元损伤或坏死的特异性指标。近已用NSE检测脑出血、脑梗死、脑肿瘤等疾病神经元损伤的程度及判断预后的重要依据。国外学者已发现癫痫持续状态(SE)患者血NSE水平升高。
Neuron-specific enolase (NSE) is mainly present in the brain neurons and neuroendocrine cells (99%), involved in the catalytic enzymes of glycolysis, NSE after neuronal injury or necrosis into the back of the brain and through Cross the blood-brain barrier into the blood. Glial cells and other tissues do not contain NSE, so NSE is a specific indicator of neuronal damage or necrosis in the brain. NSE has been used to detect cerebral hemorrhage, cerebral infarction, brain tumors and other neurological damage and determine the prognosis of an important basis. Foreign scholars have found that patients with status epilepticus (SE) blood NSE levels.