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目的探讨健康体检人群上消化道疾病相关因素的特征。方法收集2011年4月至2012年4月本中心2 280例健康体检人群的电子胃镜结果,对性别、年龄、吸烟饮酒史、非甾体类抗炎药物服用史、饮食生活习惯、上消化道疾病种类、幽门螺杆菌(Helicobacter Pylori,Hp)感染情况等因素进行回顾性分析。结果 2 280例健康体检人群包括男性1 775例,女性505例,41～50岁最多,占58.64%。共检出各种上消化道疾病2 579例次,其中各种慢性胃炎1 906例次(73.90%),十二指肠球炎217例次(8.41%),消化道溃疡189例次(占7.33%,包括胃溃疡74例,十二指肠球部溃疡115例,复合型溃疡未检出),反流性食管炎176例次(6.82%),胃、十二指肠息肉35例次(1.36%),腺上皮不典型增生25例次(0.97%),Barrett食管20例次(0.78%),霉菌性食管炎5例次(0.19%),胃癌4例次(0.16%),食管癌2例次(0.08%)。有吸烟饮酒史者1 595例(69.96%),非甾体类抗炎药物服用史者632例(27.72%),不良饮食生活习惯者1 953例(85.66%),Hp阳性者1 342例(58.86%),Hp感染率与受检者性别、年龄比较无统计学意义(P>0.05)。其中消化道溃疡Hp感染率最高(76.72%),其次是十二指肠球炎(63.59%),反流性食管炎(61.36%),Hp感染率均明显高于慢性胃炎(38.04%),组间差异有统计学意义(P<0.01)。结论健康体检人群上消化道疾病发生率高,吸烟饮酒史、非甾体类抗炎药物服用史、不良饮食生活习惯、Hp感染等是危险因素,应重视对健康体检人群的胃镜检查,健康指导可降低上消化道疾病的发生。
Objective To investigate the characteristics of upper gastrointestinal diseases related to health examination population. Methods The gastroscope results of 2280 healthy people from April 2011 to April 2012 were collected. The results of gender, age, smoking and drinking history, taking history of non-steroidal anti-inflammatory drugs, eating habit, upper gastrointestinal tract Disease types, Helicobacter Pylori (Hp) infection and other factors were retrospectively analyzed. Results A total of 2 280 healthy people were enrolled in the study, including 1 775 males and 505 females, up to the age of 41 to 50 years (58.64%). A total of 2 579 cases of various upper gastrointestinal diseases were detected, including 1 906 cases of chronic gastritis (73.90%), 217 cases of duodenal inflammation (8.41%) and 189 cases of peptic ulcer 7.33%, including 74 cases of gastric ulcer, 115 cases of duodenal ulcer, complex ulcer was not detected), 176 cases of reflux esophagitis (6.82%), stomach, duodenal polyps 35 cases (1.36%), 25 cases of atypical hyperplasia of glandular epithelium (0.97%), 20 cases of Barrett’s esophagus (0.78%), 5 cases of fungal esophagitis (0.19%), 4 cases of gastric cancer (0.16% 2 cases of cancer (0.08%). There were 1 595 cases (69.96%) with history of smoking and drinking, 632 cases (27.72%) with history of taking nonsteroidal anti-inflammatory drugs, 1 953 (85.66%) with poor eating habit, and 1 342 cases with Hp positive 58.86%). The infection rate of Hp was not significantly different from the gender and age of the subjects (P> 0.05). The prevalence rate of Hp in peptic ulcer was the highest (76.72%), followed by duodenal inflammation (63.59%), reflux esophagitis (61.36%), Hp infection rate was significantly higher than chronic gastritis (38.04%), There was significant difference between groups (P <0.01). Conclusions The prevalence of upper gastrointestinal diseases, smoking and drinking history, taking history of non-steroidal anti-inflammatory drugs, bad eating habit and Hp infection are the risk factors in the healthy physical examination population. Gastroscopy, health guidance Can reduce the incidence of upper gastrointestinal diseases.