结节病(sarcoidosis,或译炎肉瘤病)是一种慢性全身性肉芽肿,偶可侵犯喉部,若病变发展则可发生呼吸道梗阻。作者报告4例喉结节病合并呼吸道梗阻,并复习了文献,对其有关问题进行了讨论。结节病的原因尚不明,可侵犯全身除肾上腺以外的所有组织和器官,好发部位有皮肤、淋巴结、骨、肺、脾、肝、眼色素层、腮腺和泪腺。发病年龄多在20～50岁,60岁以上病变常可停止发展。由于所侵犯部位的局部反应不同,故其临床表现也各异。多数病人可有体重减轻、疲劳、呼吸困难、咳嗽和胸痛等全身症状。发生于头颈部者:约1/3眼色素层炎者合并有腮腺炎(色素层腮腺热),并先有全身性表现。面部皮肤、鼻粘膜、鼻咽、舌、口腔、喉 Sarcoidosis (sarcoidosis) is a chronic systemic granuloma that can invade the larynx and can develop respiratory obstruction if the lesion develops. The authors report four cases of laryngeal sarcoidosis with airway obstruction and reviewed the literature and discussed its related issues. The cause of sarcoidosis is not yet known. It can invade all tissues and organs except the adrenal system. Skin, lymph nodes, bone, lung, spleen, liver, uveal layer, parotid gland and lacrimal gland are the predilection sites. More than the age of onset in 20 to 50 years of age, 60 years of age can often stop the development of the disease. Because of the different parts of the site of the response, so its clinical manifestations are also different. Most patients may have generalized symptoms of weight loss, fatigue, dyspnea, cough and chest pain. Occurred in the head and neck were: about 1/3 of the uveitis with mumps parotitis (pigment parotid gland heat), and the first systemic manifestations. Facial skin, nasal mucosa, nasopharynx, tongue, mouth, throat