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患者,女性,23岁,因雷诺氏现象,关节疼痛,末节指骨变短一年余于1984年10日30日入院。既往无肝炎病史。查体:一般情况好,面部及双手皮肤发亮,张力小,不易捏起。浅表淋巴结不大。右食指,左拇指,食指末端缩短。入院时检查 GPT 正常,血沉56mm/hr,血清类风湿因子阳性,免疫复合物0.07/450波长,γ球蛋白35.2%,双手 X 片示右食指,左拇指、食指末端骨质吸收。右前臂皮肤活检显示表皮轻度萎缩,基层色素增加,真皮胶原纤维明显增生、肿胀,确诊为进行性系统性硬化症。
Patients, women, 23 years old, due to Raynaud’s phenomenon, joint pain, the distal phalanx shortened more than a year in 1984 on the 10th 30 admitted. No past history of hepatitis. Physical examination: the general situation is good, face and hands shiny skin, tension is small, not easy to pick up. Superficial lymph nodes are not. Right index finger, left thumb, index finger ends shortened. Normal GPT on admission, ESR 56 mm / hr, positive serum rheumatoid factor, 0.07 / 450 wavelength of immunocomplex, 35.2% of gamma globulin, X-ray on both hands showed the right index finger, left thumb and the distal end of the index finger. Right forearm skin biopsy showed mild epidermal atrophy, increased primary pigment, dermal collagen fibers significantly proliferated, swollen, diagnosed with progressive systemic sclerosis.