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乙型肝炎 ( HB)病毒表面抗原 ( HBs Ag)的抗原决定簇“a”是各亚型共同有的 ,它与两对亚型决定簇 ( d和 y,w和 r)共同组成 HB-s Ag各亚型。作者从细胞水平对人类 B细胞产生抗 - HBs的亚型特异性进行研究。 对 4 5名 HBs Ag、抗 - HBc和抗 - HBs均阴性的健康成人 ,全程接种 3
The antigenic determinant “a” of the hepatitis B virus surface antigen (HBsAg) is common to all subtypes and constitutes HB-s together with two pairs of subtype determinants (d and y, w and r) Ag subtypes. The authors studied the subtype specificity of anti-HBs produced by human B cells at the cellular level. Forty-five healthy adults with negative HBs Ag, anti-HBc and anti-HBs were vaccinated 3