1.治疗重症脑外伤、降低颅高压 头部外伤常并发BE及颅高压,ICP上升则CBF减少,导致广泛的脑缺血缺氧或合并脑疝。巴比妥类用于控制各种原因的颅高压,特别是脑外伤,已经取得较寿肯定的临床效果。山口指出47例脑外伤病人,在不使用任何渗透性利尿剂的情况下,应用巴比妥类ICP控制亦颇为良好,生存率也比意识水平相似的其他 1. Treatment of severe traumatic brain injury and reduce head trauma often complicated by BE and intracranial hypertension, ICP increased CBF decreased, leading to extensive cerebral ischemia and hypoxia or merger herniation. Barbiturates for the control of various causes of intracranial hypertension, especially traumatic brain injury, has made longevity certainly clinical results. Yamaguchi pointed out that in 47 patients with traumatic brain injury, the use of barbiturate-based ICP was also well controlled without any osmotic diuretics and had a similar survival rate as the conscious level