优化穿山龙乙醇动态连续提取工艺。通过单因素试验对乙醇浓度、液料比、回流速度、回流时间等进行了筛选,利用Central Composite Design响应面设计优化试验,以干浸膏得率和薯蓣皂苷含量作为评价指标,利用响应面对干浸膏得率进行了分析,支持向量回归(SVR)对薯蓣皂苷含量进行了分析。根据单因素试验结果确定了各因素对提取效果的影响,并确定了相应工艺范围。 Optimize the dynamic extraction process of Alexandrium tricolor ethanol. The concentration of ethanol, the ratio of liquid to liquid, the reflux rate, the reflux time and so on were screened by single factor experiment. The Central Composite Design response surface design optimization test was used to evaluate the dry extract yield and diosgenin content. Dry extract yield was analyzed, support vector regression (SVR) analysis of diosgenin content. According to the results of single factor test, the influence of various factors on the extraction effect was confirmed and the corresponding process range was determined.