复发性多软骨炎(Relapsing polychondritis)是一个侵犯全身软骨累及广泛器官和组织的全身性炎性疾病。曾被命名为慢性萎缩性多软骨炎,弥漫性多软骨周围炎,全身性软骨软化。1923年Jaksch-Wartenhort首次描述一个32岁的男性病人,具有多数性关节炎、发热、耳廓肿胀、鼻畸形、听力减退等表现,认为系全身性软骨病,使用了多数性软骨炎的命名。1960年Pearson报告2例,复习文献报告共27例,称为复发性多软骨炎。其后,Kaye等(1964)报告14例病人的临床和病理特点。Dolan等(1966)报告2例,复习文献共49例,详细地介绍本病的局部和全身表现,并探讨了发病原因。Daly Relapsing polychondritis is a systemic inflammatory disease that affects whole body cartilage and affects a wide range of organs and tissues. Have been named chronic atrophic polychondritis, diffuse peri-cartilage inflammation, systemic cartilage softening. 1923 Jaksch-Wartenhort first described a 32-year-old male patient with the majority of arthritis, fever, ear swelling, nasal deformity, hearing loss and other performance, that is a generalized rickets, the use of most of the names of sexitis. Two cases were reported in Pearson in 1960 and 27 cases were reviewed in literature, which is called recurrent polychondritis. Subsequently, Kaye et al. (1964) reported the clinical and pathological features of 14 patients. Dolan et al (1966) reported 2 cases, a review of a total of 49 cases of literature, a detailed description of the local and systemic manifestations of the disease, and explore the causes. Daly