Graves突眼(GO,浸润性突眼)可能是一种独立的自身免疫性疾病,虽然常与Graves病伴发,但已知的甲状腺自身抗体(TSI、TBII、TmAb、TgAb)及 TSH与GO并非有关。近几年,国外有人发现GO患者血清中存在抗眼肌细胞膜蛋白抗体,简称眼肌抗体(EMAb),其意义越来越受到重视。至今,国内尚未有EMAb的报道,我们以猪眼球后肌经差速超速离心提取眼肌膜蛋白抗原,用酶标的葡萄球菌A蛋白为抗抗 Graves (GO, infiltrating exophthalmos) may be an independent autoimmune disease, although often associated with Graves disease, but known thyroid autoantibodies (TSI, TBII, TmAb, TgAb) and TSH and GO Not relevant. In recent years, some people in foreign countries found that there is anti-ophthalmocyte membrane protein antibody in serum of GO patients, which is referred to as EMAb for short, and its significance is getting more and more attention. So far, there is no report of EMAb in our country. We extracted the ocular myosin protein antigens by differential speed ultracentrifugation of porcine posterior myocutaneous muscle and anti-staphylococcal protein A