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目的比较中西医结合方法与激素治疗结核性渗出性胸膜炎的临床效果。方法将符合结核性渗出性胸膜炎诊断的128例患者按照随机数字表法分为对照组和观察组,每组64例。2组患者均常规给予胸腔穿刺抽液治疗,在此基础上对照组给予西医抗结核药物及激素治疗,观察组给予中西医结合方法治疗。2组疗程均为6个月。比较治疗6个月后2组患者治疗总有效率,监测治疗过程中胸部影像学变化(以胸部CT及胸水彩超为手段)及不良反应发生情况。结果治疗6个月后观察组患者治疗总有效率与对照组患者相当(P>0.05);2组间胸水消退时间比较差异无统计学意义(P>0.05)。观察组不良反应发生率明显小于对照组(P均<0.05)。结论中西医结合治疗结核性渗出性胸膜炎临床效果满意,不良反应轻微,可代替激素治疗。
Objective To compare the clinical efficacy of traditional Chinese and western medicine and hormone treatment of tuberculous exudative pleurisy. Methods According to the random number table, 128 patients who met the diagnosis of tuberculous exudative pleurisy were divided into control group and observation group, with 64 cases in each group. Two groups of patients were routinely given thoracentesis aspiration therapy. On the basis of this, the control group was given anti-TB drugs and hormone therapy, and the observation group was treated by the combination of TCM and Western medicine. Two groups of treatment were 6 months. The total effective rate was compared between the two groups after 6 months of treatment. The changes of the thoracic images during the course of treatment were monitored (chest CT and pleural effusion) and the incidence of adverse reactions. Results After 6 months of treatment, the total effective rate of treatment group was similar to that of the control group (P> 0.05). There was no significant difference between the two groups in the subsidence time of pleural effusion (P> 0.05). The incidence of adverse reactions in observation group was significantly lower than that in control group (all P <0.05). Conclusion Integrative treatment of tuberculous exudative pleurisy clinical results were satisfactory, minor adverse reactions, instead of hormone therapy.