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目的分别对儿童危重症患者血浆胶体渗透压、总渗透压与预后的关系进行研究,探讨与危重症患者预后的关系。方法回顾性分析2006年1月至2012年6月入住哈尔滨医科大学附属第一医院重症监护病房(ICU)与儿科重症监护病房(PICU)的187例患者,依据其入院时的血浆胶体渗透压与总渗透压的测定值分别进行分组,计算病死率,并且进行统计学比较。血浆胶体渗透压以20mmHg(即1.2mOsm/kgH2O)为界分为两组。总渗透压以260mOsm/kgH2O与283mOsm/kgH2O为界分为三组。结果低胶体渗透压患儿与正常胶体渗透压患儿相比,病死率高(62.3%vs.20.9%,P<0.01);而在总渗透压分析中,低总渗透压患儿与正常渗透压患儿相比,病死率无统计学差异(41.82%vs.27.35%,P>0.05)。结论儿童危重症患者血浆胶体渗透压与患儿预后关系更为密切。
Objective To study the relationship between colloid osmotic pressure, total osmotic pressure and prognosis in children with critical illness, and to explore the relationship with the prognosis of critically ill patients. Methods A retrospective analysis of 187 patients admitted to intensive care unit (ICU) and pediatric intensive care unit (PICU) from the first affiliated hospital of Harbin Medical University from January 2006 to June 2012 was conducted. According to their plasma colloid osmotic pressure Total osmolality were measured values were grouped, calculated mortality, and for statistical comparison. The plasma colloid osmotic pressure is divided into two groups by 20 mmHg (ie, 1.2 mOsm / kgH2O). Total osmolality was divided into three groups with 260 mOsm / kg H 2 O and 283 mOsm / kg H 2 O. Results The children with low colloid osmotic pressure had a higher case fatality rate (62.3% vs.20.9%, P <0.01) than those with normal colloid osmotic pressure. In the total osmotic pressure analysis, There was no significant difference in case fatality rate between children and children (41.82% vs.27.35%, P> 0.05). Conclusion Children’s critically ill patients with colloid plasma osmotic pressure and prognosis of children more closely.