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磷化鋅中毒机制如何?怎样解救?可否用二巯基丙醇(BAL)或派姆(PAM)治疗? 磷化鋅是常用的毒鼠药,人誤服、吸入其分解气体(PH_3)或污染皮肤而至吸收,皆可引起中毒。对人的致死量約为0.2~0.5克(有的文献記載为0.972克)。人誤服本药后,在胃中与胃酸作用产生磷化氢气体,对胃腸粘膜有腐蝕作用,引起腹部不适、恶心、呕吐、胃灼热剧痛、口渴感、腹泻等,吸收后产生全身中毒症状:疲怠、恶寒、发烧(体溫常达38~40℃)、耳鸣、头暈、后脑部疼痛、胸部压迫感、呼吸困难、咳嗽,中枢神經系統先兴奋后抑制,故出現煩躁、手足抽搐,严重时出現惊厥
How to rescue zinc phosphide? How to rescue? Whether the use of dimercaptopropanol (BAL) or Pam (PAM) treatment? Zinc phosphate is a commonly used poison rat poisoning, inhalation of its decomposition gas (PH 3) or pollution Skin and absorption, can cause poisoning. The lethal dose to humans is about 0.2-0.5 gram (some literature records 0.972 gram). People mistakenly take the drug, in the stomach and stomach acid produce phosphine gas, gastrointestinal mucosa corrosion, causing abdominal discomfort, nausea, vomiting, heartburn pain, thirst, diarrhea, etc., after absorption of the body Symptoms of poisoning: fatigue, aversion to cold, fever (body temperature often up to 38 ~ 40 ℃), tinnitus, dizziness, after the brain pain, chest pressure, breathing difficulties, cough, central nervous system first excited after inhibition, it appears irritability , Hand-foot convulsions, convulsions in severe cases