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目的 :了解基层综合性医院口服降血糖药物的应用情况 ,为临床合理使用药物及药品的采购供应提供参考。方法 :从医院信息管理系统中调出 5年来我院所有口服降血糖药的出库数量和零售金额 ,设定日限定剂量 (DDD值 )并计算出用药人次 (DDDs) ,通过各药物的DDDs排序及金额排序等进行口服降血糖药临床应用情况分析。结果 :2 0 0 2年我院口服降血糖药DDDs排前 3位的是格列本脲 ,二甲双胍和苯乙双胍。 5年中 ,DDDs一直增加的是格列本脲、二甲双胍、苯乙双胍、格列齐特 ,而甲磺丁脲则呈下降趋势。新的口服降血糖药的临床应用正在上升但还有待开发。结论 :我院口服降血糖药的使用基本合理。糖尿病病人、口服降血糖药品种和数量均有增加趋势。
Objective: To understand the application of oral hypoglycemic drugs in primary general hospitals and to provide reference for the rational procurement of drugs and medicines for clinical use. Methods: From the hospital information management system to recall all the oral hypoglycemic agents out of the hospital in the past 5 years and the amount of retail sales, set the daily limit dose (DDD value) and calculate the number of drug users (DDDs), through the DDDs of drugs Sort and order of the amount of oral hypoglycemic agents for clinical application analysis. Results: The top 3 DDDs in oral hypoglycemic agents in our hospital in 2002 were glibenclamide, metformin and phenformin. DDDs have been increasing for 5 years with glibenclamide, metformin, phenformin, and gliclazide, while metoxicamide showed a decreasing trend. The clinical application of new oral hypoglycemic agents is on the rise but remains to be developed. Conclusion: The use of oral hypoglycemic agents in our hospital is basically reasonable. Diabetes patients, oral hypoglycemic agents and the number of increasing trend.