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目的探讨C反应蛋白(CRP)、外周血白细胞计数(WBC)及中性粒细胞计数(NEU)对冠心病严重程度的关系。方法选择急性冠脉综合症(AMI)53例(A组)、不稳定性心绞痛(UA)58例(B组)、稳定型心绞痛(SA)72例(C组)及非冠心病对照者52例(D组),分别检测、比较各组间CRP、WBC及NEU水平差异。结果急性心肌梗死组(AMI)组的CRP、WBC及NEU水平均显著高于不稳定性心绞痛组(UA)、SA组及对照组(P<0.01),AMI、UA组的3项指标水平亦显著高于对照组(P<0.05)。结论冠心病患者血清CRP及外周血WBC比健康人高,根据患者血清CRP及外周血WBC可评估临床冠心病患者病情严重程度,对疾病的危险分层和预后判断具有重要的临床价值。
Objective To investigate the relationship between the severity of coronary heart disease (CHD) and C reactive protein (CRP), peripheral blood leukocyte count (WBC) and neutrophil count (NEU). Methods Fifty-three patients with AMI (group A), 58 patients with unstable angina (group U), 72 patients with stable angina (group C) and 52 patients with non-coronary heart disease Cases (group D) were detected and compared between groups CRP, WBC and NEU levels differences. Results The levels of CRP, WBC and NEU in acute myocardial infarction (AMI) group were significantly higher than those in unstable angina pectoris group, SA group and control group (P <0.01) Significantly higher than the control group (P <0.05). Conclusion Serum CRP and WBC in patients with coronary heart disease are higher than those in healthy people. Serum CRP and peripheral blood WBC can be used to assess the severity of clinical coronary heart disease in patients with coronary heart disease, which has important clinical value in risk stratification and prognosis.