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磺脲类药物 (ｓｕｌｆｏｎｙｌｕｒｅａ ,ＳＵ)在临床上广泛用于 2型糖尿病的治疗 ,尽管磺脲类药物的作用机制目前认为主要通过刺激胰腺 β细胞分泌胰岛素 ,提高糖尿病患者外周组织对胰岛素的敏感性来发挥其疗效 ,但磺脲类药物作用的分子机制还有很多尚需阐明的环节。 2 0世纪
Sulfonylurea (SU) is clinically widely used in the treatment of type 2 diabetes. Although the mechanism of action of sulfonylureas is currently believed to increase insulin sensitivity in peripheral tissues of diabetic patients by stimulating pancreatic β-cells to secrete insulin mainly To play its efficacy, but the molecular mechanism of the role of sulfonylurea still need to be elucidated many links. 20th Century