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目的 :研究喉癌患者中抑郁程度对其预后的影响。方法 :采用Zung抑郁自评量表对我科 1999～ 2 0 0 0年 113名喉癌患者进行问卷调查 ,并研究不同抑郁程度与生存期之间的相关性。结果 :43 4%( 4 9/113 )的患者存在不同程度的抑郁状态 ,其中轻度抑郁 10 6%( 12 /113 )、中度抑郁 2 4 8%( 2 8/113 )、重度抑郁 8%( 9/113 ) ,平均随访时间 3 7个月。无抑郁组生存期明显大于中、重度抑郁组 (P <0 .0 1)。结论 :在喉癌患者的治疗中应充分重视抑郁的早期诊断和治疗。
Objective: To investigate the effect of depression on the prognosis in patients with laryngeal cancer. Methods: A total of 113 laryngeal cancer patients in our department from 1999 to 2000 were surveyed by Zung depression self-rating scale. The correlation between different degrees of depression and survival was studied. Results: 43 4% (4 9/113) patients had different degrees of depression, of which 10 6% (12/113) mild depression, 24.8% (28/113) mild depression, 8 severe depression % (9/113), the average follow-up time of 37 months. The survival of non-depression group was significantly higher than that of moderate and severe depression group (P <0.01). Conclusion: In the treatment of laryngeal cancer patients should pay full attention to the early diagnosis and treatment of depression.