雷公藤(Tripterygium WilfordiiHooK)系卫茅科植物,经去皮的根中精制而成为浸膏片或煎剂。具有清热、解毒、消积、杀虫止血等作用。该药在临床上治疗小儿难治性肾病综合征有一定疗效,应用中可引起食欲不振、恶心呕吐,少数病人可出现白细胞及血小板减少,但未见影响红细胞系的报导。我们在临床应用中发现片剂引起红细胞系抑制作用,现报告如下: 患儿男,10岁,患肾病综合征6年,病情反复发作,曾多次进行强的松长程治疗及免疫抑制剂联合治疗,疗效不显著,故于1985年12月改服用泰安制药厂生产的雷公藤片,按每日每公斤体重1.5mg,分2—3次口服。服用前,尿蛋白(++)～(+++),血象:白 Tripterygium Wilfordii HooK is a Dermatophagoides plant that is refined from a peeled root to become an extract patch or decoction. With heat, detoxification, consumer product, insecticide to stop bleeding and so on. The drug in the clinical treatment of children with refractory nephrotic syndrome has a certain effect, application can cause loss of appetite, nausea and vomiting, a small number of patients may appear leukopenia and thrombocytopenia, but no reports of the impact of red blood cells. We found in clinical application of tablet-induced inhibition of erythrocyte lineage, are as follows: Children male, 10 years old, suffering from nephrotic syndrome for 6 years, the disease recurrent, has repeatedly long-term treatment with prednisone and immunosuppressive agents Treatment, curative effect is not significant, so in December 1985 changed the use of Tai’an Pharmaceutical Factory production Tripterygium tablets, according to the daily weight per kilogram of 1.5mg, points 2-3 times orally. Before taking, urine protein (++) ~ (+++), blood: white