论文部分内容阅读
目的:探讨亚胺培南西司他丁不同输注持续时间治疗重症肺炎的价值。方法:收集2013年2月~2015年12月我院诊断为重症肺炎的患者,随机分为:研究组(亚胺培南西司他丁0.5/2h输注q6h给药24h)和对照组(亚胺培南西司他丁0.5/0.5h输注q6h,24h)。结果:①研究组和对照组重症肺炎治疗疗效分别为96%、84%,比较有差异(P<0.05)。②两组治疗前CRP及PCT水平比较无差异(P>0.05);两组治疗后CRP及PCT水平比较有差异(P<0.05)。结论:亚胺培南西司他丁0.5/2h输注q6h的延长输注时间治疗方案有助于提高重症肺炎的治疗疗效,减轻体内炎症水平。
Objective: To investigate the value of imipenem and cilastatin for different durations of infusion in the treatment of severe pneumonia. Methods: The patients diagnosed as severe pneumonia in our hospital from February 2013 to December 2015 were randomly divided into study group (imipenem cilastatin 0.5 / 2h infusion q6h for 24 hours) and control group Amoxicillin and Cilastatin 0.5 / 0.5h infusion q6h, 24h). Results: ① The therapeutic effects of severe pneumonia in study group and control group were 96% and 84%, respectively (P <0.05). ② There was no difference in CRP and PCT levels between the two groups before treatment (P> 0.05). CRP and PCT levels were significantly different between the two groups after treatment (P <0.05). Conclusion: Imipenem and cilastatin 0.5 / 2h infusion of q6h prolonged infusion time treatment program will help to improve the treatment of severe pneumonia and reduce the level of inflammation in vivo.