我们对接受自血光量子疗法治疗的颅脑损伤病人外周血脆性位点（ＦＳ）进行分析，并与正常人做对照。结果对照组与实验组治疗前比较无显著性差异（Ｐ＞０．０５）。说明此病与ＦＳ无关。实验组治疗后３年与治疗前比较有显著性差异（Ｐ＜０．０５）；治疗结束时与治疗前比较有高度显著性差异（Ｐ＜０．０１）。治疗后３年与治疗结束时有显著性差异（Ｐ＜０．０５）。前二者说明ＦＳ的升高与紫外线照射血液回输有关，后者说明３年后ＤＮＡ有恢复趋势。 We analyzed the peripheral blood fragility (FS) of patients with craniocerebral injury treated with quantum ophthalmic therapy and compared them with normal controls. Results There was no significant difference between the control group and experimental group before treatment (P> 0.05). This shows that the disease has nothing to do with FS. The experimental group 3 years after treatment compared with before treatment were significantly different (P <0.05); at the end of treatment compared with before treatment there was a highly significant difference (P <0.01). Three years after treatment and the end of treatment were significantly different (P <0.05). The first two indicate that the increase of FS is related to the UV irradiation and blood transfusion, the latter shows that the DNA has a recovery trend after 3 years.