在有机合成中氯代铬酸吡啶盐(PCC)是将醇氧化为羰基化合物的极佳选择性氧化剂,它是1899年合成的。但此试剂直到1975年Corey等首次将它成功地用于有机合成以后才受到了越来越广泛的注意。寻找一种温和的、用途广的、有选择性的,且便于将醇氧化成羰基化合物的试剂,是许多实验室共同关心的课题。曾研究了许多铬(Ⅵ)离子的试剂,可是其中的大多数都不适用于现代有机合成,尤其是复杂或不稳定物质 Chlorinated pyridinium chlorochromate (PCC) is an excellently selective oxidant for the oxidation of alcohols to carbonyl compounds, which was synthesized in 1899. However, this reagent was not paid more and more attention until after it was successfully used in organic synthesis by Corey et al. For the first time in 1975. Finding a mild, versatile and selective reagent that facilitates the oxidation of alcohols to carbonyls is a common concern in many laboratories. Many reagents of chromium (VI) have been studied, but most of them are not suitable for modern organic synthesis, especially for complex or unstable materials