Evolving management of metaplasia and dysplasia in Barrett's epithelium

来源 :World Journal of Gastroenterology | 被引量 : 0次 | 上传用户:z957558481
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Oesophageal cancer affects more than 450000 people worldwide and despite continued medical advancements the incidence of oesophageal cancer is increasing. Oesophageal cancer has a 5 year survival of 15%-25% and now globally attempts are made to more aggressively diagnose and treat Barrett’s oesophagus the known precursor to invasive disease. Currently diagnosis the of Barrett’s oesophagus is predominantly made after endoscopic visualisation and histopathological confirmation. Minimally invasive techniques are being developed to improve the viability of screening programs. The management of Barrett’s oesophagus can vary greatly dependent on the presence and severity of dysplasia. There is no consensus between the major international medical societies to determine and agreed surveillance and intervention pathway. In this review we analysed the current literature to demonstrate the evolving management of metaplasia and dysplasia in Barrett’s epithelium. Oesophageal cancer affects more than 450000 people worldwide and despite continued medical advancements the incidence of oesophageal cancer is increasing. Oesophageal cancer has a 5-year survival of 15% -25% and now globally attempted to more aggressively diagnose and treat Barrett’s oesophagus the known precursor to invasive disease. Currently diagnosis of of oesophagus is predominantly made after endoscopic visualization and histopathological confirmation. Minimally invasive techniques are being improved to the viability of screening programs. The management of Barrett’s oesophagus can vary greatly dependent on the presence and severity of There is no consensus between the major international medical societies to determine and agreed surveillance and intervention pathway. In this review we analyze the current literature to demonstrate the evolving management of metaplasia and dysplasia in Barrett’s epithelium.
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