论文部分内容阅读
目的：测定鼻咽癌患者放射治疗前后可溶性白细胞介素－２受体水平。方法：测定了５５例鼻咽癌患者血清可溶性白细胞介素－２受体（ｓＩＬ－２Ｒ）水平治疗前后的变化并与３５例健康成人对照。结果：鼻咽癌患者血清ｓＩＬ－２Ｒ水平较正常对照明显升高，治疗后１个月、３个月及６个月逐渐下降，治疗后６个月血清ｓＩＬ－２Ｒ水平回升预示肿瘤的复发转移。结论：提示ｓＩＬ－２Ｒ可作为鼻咽癌临床诊断病情监测又一新的免疫生物学指标。
Objective: To determine the level of soluble interleukin-2 receptor in patients with nasopharyngeal carcinoma before and after radiation therapy. METHODS: Changes in levels of serum soluble interleukin-2 receptor (sIL-2R) in 55 patients with nasopharyngeal carcinoma before and after treatment were determined and compared with 35 healthy adults. Results: Serum sIL-2R levels in patients with nasopharyngeal carcinoma were significantly higher than those in normal controls, and gradually decreased at 1 month, 3 months, and 6 months after treatment. Serum sIL-2R levels rose at 6 months after treatment, indicating that tumors relapsed and metastasized. . Conclusion: It is suggested that sIL-2R may serve as a new immunobiological marker for the clinical diagnosis of nasopharyngeal carcinoma.