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用中和试验法和间接酶标染色法(简称免疫酶法)检测了30例宫颈癌病人和30例正常妇女血清中HSV—1和HS—2抗体的活性。宫颈癌病人遭受HSV—2感染的阳性率显著高于正常妇女。宫颈癌病人HSV—1和HSV—2抗体的几何平均滴度显著高于相应的正常妇女。免疫酶法检测HSV抗体远比中和试验法敏感。
The activity of HSV-1 and HS-2 antibodies in sera of 30 patients with cervical cancer and 30 normal women were detected by neutralization assay and indirect enzyme-linked immunosorbent assay (ELISA). Cervical cancer patients suffered HSV-2 infection was significantly higher than the normal rate of women. The geometric mean titers of HSV-1 and HSV-2 antibodies in cervical cancer patients were significantly higher than those of corresponding normal women. Immunoenzymatic detection of HSV antibodies is far more sensitive than the neutralization assay.