维生素E(VE)不足常伴发血小板聚集增加,后者可通过补充VE而恢复正常化。糖尿病人所存在的血小板TXA_2生成增加,却可通过降低血小板VE含量而得到纠正。因此,本文作者采用双盲、安慰剂对照交叉试验,给22例无大血管病变和无/或极轻度微血管病的IDDM患者服用400mg消旋-α-醋酸VE/d,共4周,然后观察其对ADP与胶原 Insufficient vitamin E (VE) is associated with an increase in platelet aggregation, which can be normalized by vitamin E supplementation. The presence of TXA 2 in platelets in diabetic patients increases, but can be corrected by lowering the platelet VE content. Therefore, we used a double-blind, placebo-controlled crossover trial in 22 patients with idiopathic-alpha-acetic acid VE / d in 22 IDDM patients without macroangiopathy and / or minimally invasive microvascular disease for 4 weeks and then Observe its effect on ADP and collagen